Cole Palmer is set for a longer spell on the sidelines after suffering a fractured toe following an accident at home, BBC reported.
The 23-year-old had been due to return to team training this week after two months out with a groin issue, but he has now had an injury set-back after stubbing his toe on a door during the night.
Before the international break, it had been hoped he would be able to feature against Barcelona in the Champions League on Tuesday night, but he will now miss that game, plus Premier League matches against Burnley and leaders Arsenal.
"He is probably not available for Saturday for sure, Barcelona for sure or Arsenal for sure," said boss Enzo Maresca in his pre-match news conference.
Palmer has not played for the Blues since their 2-1 defeat by Manchester United on 20 September.